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Search Results for " 5-ht1a receptor "

20

Compounds

Cat No. Product Name Synonyms Targets
T37197 5-HT1A modulator 2 hydrochloride 5-HT Receptor
5-HT1A modulator 2 hydrochloride, a derivative of 8-OH-DPAT , is a modulator of 5-HT1A with a Ki of 53 nM for 5-HT1A binding[1]. [1]. Naiman, N.,et al. 2-(Alkylamino)tetralin derivatives: interaction with 5-HT1A serotoni...
T0280 Spiperone Spiroperidol,Spiropitan Dopamine Receptor
Spiperone (Spiropitan) is a spiro butyrophenone analog similar to HALOPERIDOL and other related compounds. It has been recommended in the treatment of SCHIZOPHRENIA.
TQ0311 GSK163090 Dopamine Receptor , 5-HT Receptor
GSK163090 is a specific and orally active 5-HT1A/B/D receptor antagonist (pKis: 9.4/8.5/9.7, and 6.3/6.7 for 5-HT1A/B/D, and dopamine D2/D3).
T9272 Xaliproden hydrochloride Dopamine Receptor , 5-HT Receptor
Xaliproden is a compound that mimics the effects of nerve growth factor and is also a serotonin 5-HT1A receptor agonist.
T21011 Buspirone Buspirone free base,Ansial 5-HT Receptor
Buspirone (Buspirone free base) is an azaspiro compound which has a role as an anxiolytic drug, a sedative, a serotonergic agonist and an EC 3.4.21.26 (prolyl oligopeptidase) inhibitor.
T0162 Quetiapine ICI204636,Quetiapin Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor , AChR , Histamine Receptor
Quetiapine (ICI204636) is used for the therapy of schizophrenia, and for the treatment of acute manic episodes associated with bipolar I disorder. The mechanism of quetiapine' action is thought by mediated through antago...
T2132 Buspirone hydrochloride Buspirone HCl,Narol,Buspar Dopamine Receptor , 5-HT Receptor
Buspirone hydrochloride (Buspar) is a 5HT(1A) receptor agonist, used to treat generalized anxiety disorder (GAD).
T8593 RU 24969 5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole 5-HT Receptor
RU 24969 (5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole) is a selective agonist of 5-HT1A and 5-HT1B receptors.
T22236 Alprenolol hydrochloride 5-HT Receptor
Alprenolol hydrochloride is a non-selective blocker of beta, and also is a antagonist of5-HT1A receptor.
T3046 BMY 7378 dihydrochloride BMY7378 HCl Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
BMY 7378 dihydrochloride (BMY7378 HCl) , α1D-adrenergic receptor antagonist, is a weak partial agonist/antagonist of 5-HT1A receptor.
T6241 Quetiapine hemifumarate Quetiapine Fumarate,ICI-204636 Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
Quetiapine hemifumarate (ICI-204636), an atypical antipsychotic, is used in the treatment of bipolar I mania, schizophrenia, bipolar II depression, bipolar I depression.
T8136 Perospirone hydrochloride Perospirone HCl,SM-9018 hydrochloride Dopamine Receptor , 5-HT Receptor
Perospirone hydrochloride (Perospirone HCl) is an atypical antipsychotic agent for the treatment of schizophrenia. It also displays affinity towards 5HT1A receptors as a partial agonist.
T1045 Trimipramine maleate Surmontil maleate Dopamine Receptor , 5-HT Receptor , Antibacterial , Adrenergic Receptor , Norepinephrine , Histamine Receptor
Trimipramine maleate (Surmontil maleate) appears to inhibit serotonin transport and norepinephrine uptake by nerve terminals. This increases available norepinephrine or serotonin and prolongs its action. Trimipramine Mal...
T6647 Rotigotine- Neupro,N-0923,N-0437,SPM 962 Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
Rotigotine (N-0923) is a non-ergot dopamine receptor agonist used in the therapy of Parkinson disease and restless leg syndrome. Administered as a once-daily transdermal patch, Rotigotine has not been associated with ser...
T3431 Pardoprunox hydrochloride SLV-308 hydrochloride,DU-126891 hydrochloride Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor
Pardoprunox hydrochloride (SLV-308 hydrochloride) is a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist, D2 (pKi = 8.1) and D3 receptor (pKi = 8.6) partial agonist and 5-HT1A recept...
T0088 Urapidil hydrochloride Urapidil HCl 5-HT Receptor , Adrenergic Receptor
Urapidil hydrochloride (Urapidil HCl) is 5-HT1A receptor agonist and an α1-adrenoceptor antagonist.
T5387 LP-211 Dopamine Receptor , 5-HT Receptor
LP-211 is a brain penetrant selective agonist for a 5-HT7 receptor (Ki: 0.58 nM), and >300-fold selectivity over the 5-HT1A receptor.
T21337 Lurasidone SM-13496 Dopamine Receptor , 5-HT Receptor
Lurasidone (SM-13496) is an antagonist of both dopamine D2 and 5-HT7(IC50=1.68 and 0.495 nM, respectively).It also a partial agonist of 5-HT1A receptor(IC50 : 6.75 nM).
T4577 Cariprazine RGH-188 Dopamine Receptor , 5-HT Receptor
Cariprazine (RGH-188) is a novel antipsychotic drug candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM).
T12489L Pimethixene maleate Pimetixene maleate Dopamine Receptor , 5-HT Receptor , AChR , Histamine Receptor
Pimethixene maleate (Pimetixene maleate) is a potent 5-HT2B receptor antagonist with sedative and antitussive activity.Pimethixene maleate inhibits 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4 as we...

Compounds

5-HT1A modulator 2 hydrochloride
T37197
Synonym:
Target: 5-HT Receptor
Spiperone
T0280
Synonym: Spiroperidol,Spiropitan
Target: Dopamine Receptor
GSK163090
TQ0311
Synonym:
Target: Dopamine Receptor, 5-HT Receptor
Xaliproden hydrochloride
T9272
Synonym:
Target: Dopamine Receptor, 5-HT Receptor
Buspirone
T21011
Synonym: Buspirone free base,Ansial
Target: 5-HT Receptor
Quetiapine
T0162
Synonym: ICI204636,Quetiapin
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, AChR, Histamine Receptor
Buspirone hydrochloride
T2132
Synonym: Buspirone HCl,Narol,Buspar
Target: Dopamine Receptor, 5-HT Receptor
RU 24969
T8593
Synonym: 5-methoxy-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole
Target: 5-HT Receptor
Alprenolol hydrochloride
T22236
Synonym:
Target: 5-HT Receptor
BMY 7378 dihydrochloride
T3046
Synonym: BMY7378 HCl
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor
Quetiapine hemifumarate
T6241
Synonym: Quetiapine Fumarate,ICI-204636
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor
Perospirone hydrochloride
T8136
Synonym: Perospirone HCl,SM-9018 hydrochloride
Target: Dopamine Receptor, 5-HT Receptor
Trimipramine maleate
T1045
Synonym: Surmontil maleate
Target: Dopamine Receptor, 5-HT Receptor, Antibacterial, Adrenergic Receptor, Norepinephrine, Histamine Receptor
Rotigotine-
T6647
Synonym: Neupro,N-0923,N-0437,SPM 962
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor
Pardoprunox hydrochloride
T3431
Synonym: SLV-308 hydrochloride,DU-126891 hydrochloride
Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor
Urapidil hydrochloride
T0088
Synonym: Urapidil HCl
Target: 5-HT Receptor, Adrenergic Receptor
LP-211
T5387
Synonym:
Target: Dopamine Receptor, 5-HT Receptor
Lurasidone
T21337
Synonym: SM-13496
Target: Dopamine Receptor, 5-HT Receptor
Cariprazine
T4577
Synonym: RGH-188
Target: Dopamine Receptor, 5-HT Receptor
Pimethixene maleate
T12489L
Synonym: Pimetixene maleate
Target: Dopamine Receptor, 5-HT Receptor, AChR, Histamine Receptor
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TargetMol